Clinical Studies: Vita Bunch

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The research behind Vita Bunch

Guided by the science. Grown by nature.

Vita Bunch is our daily multivitamin and mineral, taken as three capsules. It supports normal energy-yielding metabolism and normal immune function, and helps maintain strong, healthy bones as you age.* Published research guided the forms and amounts one nutrient at a time: the vitamin K2 is MK-7 at the amount used in a three-year trial, and the vitamin E is the natural d-alpha form.

Each study below is published and linked, with who took part, what they took, how much, for how long and what the researchers found.

Capsules, one serving (three capsules daily): Vitamin C (from Ascorbic acid and Amla (fruit) extract) 100 mg · Vitamin E (as D-alpha tocopheryl succinate) 20 mg · Vitamin K2 (MK-7) (Menaquinone 7) 180 mcg · Vitamin B1 (as Thiamin HCl) 2.4 mg · Vitamin B2 (as riboflavin) 2.6 mg · Niacin 25 mg NE · Vitamin B6 (as pyridoxine HCl) 3.4 mg · Vitamin B12 (as methylcobalamin) 500 mcg · Biotin 1000 mcg · Pantothenic acid 30 mg · Zinc (as zinc amino acid chelate) 15 mg · Selenium (as selenomethionine) 25 mcg · Choline (as choline bitartrate) 10 mg · Whole Food Greens Complex 100 mg · Whole Food Fruit Complex 100 mg · Organic Turmeric (root) powder 50 mg · Inositol 10 mg · Lutein 10 mcg.

These are the panel lines this page discusses. The full Supplement Facts panel, including vitamins A and D3 and the other minerals, is on the product page.

Why it is built this way

K2 as MK-7, 180 mcg

Vitamin K2 comes in short-chain and long-chain forms. Vita Bunch uses MK-7, a long-chain form, at 180 mcg a serving. That is the same form and amount a Maastricht University trial gave healthy postmenopausal women every day for three years, in a study funded by the company behind the trial's MK-7.[1]

Natural vitamin E

The vitamin E is d-alpha tocopheryl succinate, the natural form. At the National Research Council of Canada, two groups of five adults took an equal mix of natural vitamin E and the all-rac form, often labeled dl-alpha, each tagged with deuterium so the two could be measured apart. After dosing ended, blood levels of the natural form ran about twice as high, and the authors concluded it has roughly twice the availability.[2] That study used the acetate form of each.

What the studies found

Multivitamins and memory

  • Mass General and Harvard, 2024: researchers pooled three placebo-controlled sub-studies of the COSMOS trial, more than 5,000 U.S. adults aged 60 and older who took a standard one-tablet daily multivitamin-mineral or a placebo for two to three years. Across all three, the multivitamin groups did better on episodic memory tests than the placebo groups (a difference of 0.06 standard deviation units, 95% CI 0.03 to 0.10, P = 0.0007). Global cognition, pooled from the two sub-studies that measured it, favored the multivitamin by 0.07 units (95% CI 0.03 to 0.11, P = 0.0009), a gap the authors put at about two years of cognitive aging.[3]
  • Disclosure: COSMOS was funded by grants from the U.S. National Institutes of Health and Mars Edge, and the multivitamin's maker supplied part of the study pills. The paper states that the funders had no role in the design or analysis.

Vitamin K2 and bone: a three-year trial at the same form and amount

  • VitaK at Maastricht University, 2013: 244 healthy postmenopausal women took 180 mcg of MK-7 a day or a placebo for three years. MK-7 slowed the age-related decline in bone mineral content and density at the lumbar spine and the neck of the thigh bone. It had no effect at the total hip.[1]
  • Disclosure: the study was funded by NattoPharma, the company behind the trial's MK-7.
  • Vitamin K plays a part in normal blood clotting. If you take a blood-thinning medication, talk with your doctor before adding vitamin K2.

What we say about Vita Bunch: it helps maintain strong, healthy bones as you age.*

B vitamins, energy and tiredness

  • European Union, 2012: after scientific review by the European Food Safety Authority, EU law authorized the statements that riboflavin, niacin, vitamin B6 and pantothenic acid each contribute "to the reduction of tiredness and fatigue," and that those four and thiamine each contribute "to normal energy-yielding metabolism." A food may carry them only if it is at least a "source of" the nutrient under EU rules.[4]
  • Emory University, 1996: nine healthy adults took single riboflavin doses of 20, 40 and 60 mg by mouth and one dose by IV, in random order. The researchers calculated that an adult can absorb at most 27 mg of riboflavin from a single dose, and urine accounted for about half of its removal from the blood.[5] Riboflavin is naturally yellow, so the share that leaves through the kidneys can turn urine bright yellow.

What we say: it supports normal energy-yielding metabolism and helps reduce tiredness and fatigue.*

Zinc, selenium and immune function

  • European Union, 2012: the same regulation authorizes "Zinc contributes to the normal function of the immune system" and the same statement for selenium, again only for foods that are at least a "source of" each mineral.[4]

What we say: it supports normal immune function.*

The other ingredients

Vitamin B12. The B12 is 500 mcg of methylcobalamin.

Vitamin C, 100 mg from ascorbic acid and amla fruit extract. Together they give you 111% of the daily value. In a 2013 University of Otago trial, 36 young men ate half a gold kiwifruit a day or took a 50 mg chewable vitamin C tablet for six weeks. Vitamin C rose in both groups, with no significant difference between them in any of the fluid, cell or tissue samples tested.[6] Zespri International, which markets gold kiwifruit, supported the study and supplied the fruit.

Biotin, 1,000 mcg. Biotin can interfere with some lab tests, so tell your doctor you take it before blood work.

Greens, fruit, turmeric, inositol, choline and lutein. The Whole Food Greens Complex (alfalfa leaf, barley grass, chlorella, spirulina and broccoli) and the Whole Food Fruit Complex (pomegranate, acai berry, blueberry, cranberry and organic goji berry) are 100 mg each. The organic turmeric root powder is 50 mg, inositol and choline are 10 mg each, and lutein is 10 mcg, each named on the panel at its own weight.

Every product's published third-party test results are on our testing page.

See Vita Bunch →

Sources

Last reviewed: September 23, 2026.

  1. Knapen MH, et al. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women. Osteoporosis International. 2013;24(9):2499-2507. PubMed 23525894. doi:10.1007/s00198-013-2325-6.
  2. Burton GW, et al. Human plasma and tissue alpha-tocopherol concentrations in response to supplementation with deuterated natural and synthetic vitamin E. The American Journal of Clinical Nutrition. 1998;67(4):669-684. PubMed 9537614. doi:10.1093/ajcn/67.4.669.
  3. Vyas CM, et al. Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial and meta-analysis of 3 cognitive studies within COSMOS. The American Journal of Clinical Nutrition. 2024;119(3):692-701. PubMed 38244989. doi:10.1016/j.ajcnut.2023.12.011.
  4. European Commission. Commission Regulation (EU) No 432/2012 of 16 May 2012 establishing a list of permitted health claims made on foods, other than those referring to the reduction of disease risk and to children's development and health. Official Journal of the European Union. 2012;L136:1-40. The quoted statements are from its Annex, based on scientific opinions of the European Food Safety Authority. EUR-Lex 32012R0432.
  5. Zempleni J, Galloway JR, McCormick DB. Pharmacokinetics of orally and intravenously administered riboflavin in healthy humans. The American Journal of Clinical Nutrition. 1996;63(1):54-66. PubMed 8604671. doi:10.1093/ajcn/63.1.54.
  6. Carr AC, et al. A randomized steady-state bioavailability study of synthetic versus natural (kiwifruit-derived) vitamin C. Nutrients. 2013;5(9):3684-3695. PubMed 24067392. doi:10.3390/nu5093684.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.